产品货号：
Z25216
中文名称：
Rkhd1/MEX3D抗体
英文名称：
Anti-Rkhd1/MEX3D Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Rkhd1/MEX3D Antibody |
| 指标别名 | MEX3,TINO,RKHD1,MEX-3D,RNF193,OK/SW-cl.4,KIAA2031,RNA-binding protein MEX3D,RING finger and KH domain-containing protein 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | MEX3D |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Rkhd1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human Rkhd1.The immunogen is located within amino acids 360 - 410 of Rkhd1. |
| 计算分子量 | 65kDa |
| 成分 | Rkhd1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Rkhd1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Rkhd1,also known as TINO or MEX3D is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module.MEX3 proteins,including Rkhd1,are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway.These proteins are a novel family of evolutionarily conserved RNA-binding proteins,differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms.Rkhd1 binds to the AU-rich element in the 3'-untranslated region of Bcl-2 mRNA and is thought to be a negative regulator of Bcl-2 expression.Rkhd3 and Rkhd4,but not Rkhd1,co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies),recently characterized as centers of mRNA turnover. |
| Uniprot ID | Q86XN8 |
| 基因名全称 | Mex-3 homolog D (C.elegans) |
| 蛋白名全称 | Mex-3 homolog D (C.elegans) |
| 推荐稀释比 | Rkhd1 antibody can be used for detection of Rkhd1 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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